On Mac OS X, Phred and Phrap can easily be compiled and run from the command line, just like on other UNIX-based systems. For users who prefer to run Phred-Phrap from a graphical user interface, and for users who would like an easy-to-use contig editor, CodonCode Corporation offers CodonCode Aligner.
CodonCode Aligner offers support for running Phred and Phrap, as well as many other commonly used functions like end clipping, vector trimming, mutation detection, and so on. Free demo and trial versions are available for downloading, and include installers of time-limited trial versions of Phred and Phrap.
Due to the widespread acceptance of OS X, CodonCode Corporation has stopped supporting the Classic Mac OS (OS 9.x).